Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months What Caused These Multiple Hyperpigmented Macules of the Mouth? Removal of lip pigmentation with our Alma Q laser. Such lip spots (aka labial melanotic macules) appear for no apparent reason. Similar spots can appear due to smoking, sun damage, drug reactions, Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Melanotic Macules, Naevi, and Melanoma Springer Nature Link Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) La Bouche Parfaite