Carnitine Shuttle Purpose and Mechanism Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Role of L carnitine in Cardiovascular Health: Literature Review Cureus Carnitine Acetyltransferase an overview ScienceDirect Topics Frontiers Fatty acid oxidation in immune function Carnitine transport and fatty acid oxidation ScienceDirect